Growth Hormone · Research kit
MK-677laboratory reference kit
aka Ibutamoren
Oral ghrelin mimetic for long-duration GH/IGF-1 research.
- Class
- Oral ghrelin mimetic (non-peptide)
- Half-life
- ~24 h
- Kit
- 10 vials
- Use
- Research only
Available on request
Get a quote for MK-677
This compound isn't in the standard 10-vial kit catalog. Message us on WhatsApp and we'll quote pricing, mg options and lead time after reviewing current availability.
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What is MK-677?
MK-677 (ibutamoren) is a non-peptide, orally bioavailable ghrelin receptor agonist used in long-duration GH/IGF-1 elevation research where parenteral dosing is impractical.
Mechanism of action
Orally bioavailable GHS-R agonist.
Primary research areas
Long-duration GH/IGF-1 elevation studies.
Research notes
- Not a peptide; included for mechanistic completeness.
MK-677: expanded research context
MK-677 (ibutamoren) is an orally active, non-peptide small-molecule agonist of the ghrelin receptor (GHS-R1a), first described in the 1990s. Although not a peptide, it is studied alongside growth-hormone secretagogue peptides such as ipamorelin, GHRP-2 and GHRP-6 because it acts on the same receptor.
Research literature focuses on its effect on pulsatile growth-hormone and IGF-1 secretion, nitrogen balance, bone-turnover markers and sleep architecture in controlled clinical-research settings. Its long half-life relative to peptide secretagogues makes it a common comparator in GHS-R pharmacology.
Regena lists MK-677 as a research reference compound on a quote basis. Contact us to confirm current availability before ordering.
Published clinical evidence
Selected peer-reviewed studies and outcome trials referenced in the MK-677 literature. Sources listed for orientation; full papers via PubMed / journal DOI.
MK-677 and GH/IGF-1 in healthy older adults
Annals of Internal Medicine · 2008
Two-year randomised trial reporting sustained increases in GH pulsatility and IGF-1 alongside changes in fat-free mass markers.
Ibutamoren in diet-induced catabolism
Journal of Clinical Endocrinology & Metabolism · 1998
Study reporting reversal of diet-induced nitrogen wasting in healthy volunteers in a controlled research setting.
MK-677 and sleep architecture
Neuroendocrinology · 1997
Report of increased stage IV and REM sleep duration in young and older subjects.
Ghrelin receptor agonist pharmacology review
Endocrine Reviews · 2000s
Overview of GHS-R1a agonists including MK-677 and peptide secretagogues, and their comparative receptor pharmacology.
Third-party COA — testing in progress
Need the batch-specific COA for your order? Email inforegenapeptides@gmail.com — we'll send it as soon as the lab returns the report (typically 5–10 business days after shipment).
Why researchers buy from Regena
HPLC ≥99% purity
Every batch independently tested. Mass spectrometry verification on every research compound. COAs on request.
10-vial kits, properly sealed
Lyophilized peptide, rubber-stoppered amber vials, batch-coded. Stable for shipping; cold storage on arrival.
Germany · USA · China hubs
Tracked delivery from the best hub for your destination and available stock. Discreet, plain packaging.
Secure SEPA bank transfer
Encrypted checkout, verified IBAN. No card details stored. Card payment links available on request.
How ordering works
- 1
Pick your MK-677 kit above
Each kit contains 10 vials. Choose your strength — bigger vials give you a lower €/mg.
- 2
Secure checkout in under 2 minutes
Add to cart, fill in shipping, get your IBAN and order reference instantly.
- 3
Pay by bank transfer (or card on request)
Bank transfer is fastest and fee-free. Need a card? Message us on WhatsApp and we'll send a payment link.
- 4
We ship within 24 hours
You get a tracking number by email + WhatsApp. EU delivery 5–18 business days. COA included on request.
Frequently asked questions
Research-use disclaimer
Information on this page is provided for educational and scientific reference purposes only. MK-677 is a research compound intended for in-vitro laboratory investigation by qualified professionals. Nothing here constitutes medical advice, dosing guidance or a recommendation for human or veterinary use. Half-life and mechanism descriptions reflect published literature approximations.
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Delivery areas
MK-677 — shipped to research hubs worldwide
Same HPLC-verified MK-677 batch, same COA — tracked delivery to laboratories and independent researchers across Europe, the UK, the USA and beyond. Pick a hub for local shipping window and currency notes.
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Regena Peptides. (2026-10-22). MK-677 — HPLC-verified research peptide. https://regena.app/peptides/mk-677
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