Growth Hormone · Synthetic Hexapeptide
Growth Hormone Releasing Peptide 5
Also known as GHRP-5
A synthetic hexapeptide and growth hormone secretagogue, GHRP-5 acts as a potent agonist of the ghrelin receptor for laboratory research.
- Length
- 6 amino acids
- Half-life
- Not well characterised
- Mechanism
- GHRP-5 is a ghrelin receptor (GHS-R1a) agonist and a potent stimulator of growth hormone secretagogue activity.
- Studied in
- Its effects on growth hormone release and related physiological pathways are investigated using in vitro cell assays and animal models.
About Growth Hormone Releasing Peptide 5
Growth Hormone Releasing Peptide 5 (GHRP-5) is a synthetic oligopeptide belonging to the GHRP family. Its structure consists of a six amino acid chain, D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2. This compound is investigated for its high affinity and selectivity for the growth hormone secretagogue receptor 1a (GHS-R1a), also known as the ghrelin receptor.
As a research compound, GHRP-5 provides a tool for studying the complex regulation of the hypothalamic-pituitary-somatotropic axis. In laboratory settings, it is used to probe the mechanisms of GH release, receptor signalling pathways, and downstream cellular responses in various cell lines and animal models.
Laboratory notes
- GHRP-5 is typically supplied as a lyophilised powder and requires reconstitution with bacteriostatic or sterile water for in vitro use.
- Store lyophilised peptide at -20°C and reconstituted solutions at 4°C for short-term stability.
- Like other GHRP analogues, its activity can be synergistic with Growth Hormone Releasing Hormone (GHRH) in certain experimental models.
Storage and reconstitution basics: storage guide.
Questions about Growth Hormone Releasing Peptide 5
What is the molecular formula of GHRP-5?
The molecular formula for Growth Hormone Releasing Peptide 5 is C45H55N9O6.
What receptor does GHRP-5 primarily target?
GHRP-5 is a selective agonist for the growth hormone secretagogue receptor 1a (GHS-R1a), the same receptor targeted by the endogenous hormone ghrelin.
Is GHRP-5 related to GHRP-6?
Yes, both are synthetic hexapeptides from the same family of growth hormone secretagogues and act on the GHS-R1a receptor, though they possess different amino acid sequences and may exhibit variations in potency in research models.
Is Growth Hormone Releasing Peptide 5 for human use?
No. It is supplied strictly for in-vitro laboratory research and is not for human or animal consumption.
Related research peptides
All products are sold for laboratory research use only. Not for human consumption, not a medicine, not for diagnosing, treating or preventing any condition.