Cognitive · Porcine-derived peptide mixture
N-PEP-12
Also known as NT-020
A porcine brain-derived mixture of short peptides studied in neuronal cell culture models for its neurotrophic-like properties.
- Length
- Mixture of short peptides (<1 kDa)
- Half-life
- Not well characterised
- Mechanism
- The precise mechanism is not fully elucidated, but it is proposed to mimic the action of endogenous neurotrophic factors in cell culture models, supporting neuronal survival and plasticity.
- Studied in
- Examined in neuronal cell culture systems to assess its effects on cell survival, differentiation, and protection against various stressors like oxidative and excitotoxic damage.
About N-PEP-12
N-PEP-12 is not a single, defined peptide but a peptone, which is a standardized, filtered enzymatic digest of porcine brain tissue. This controlled process yields a complex mixture of numerous short-chain peptides (typically under 1 kDa) and free amino acids. The composition is intended to provide a range of signaling molecules similar to those found in a neurotrophic environment.
In laboratory settings, N-PEP-12 is used as a research compound in the field of neuroscience. It is applied to neuronal cell cultures to study its effects on cellular vitality, dendritic growth, and resilience to neurotoxic insults. The aim of these studies is to investigate how this complex mixture of brain-derived peptides can modulate fundamental aspects of neuronal health and function in vitro.
Laboratory notes
- This product is a complex mixture (a peptone), not a single synthetic peptide with a defined sequence.
- The composition is standardized and controlled through a specific manufacturing process involving enzymatic hydrolysis of brain tissue.
- It is primarily used as a supplement in neuronal cell culture media to investigate its neuroprotective or neurotrophic-like effects.
Storage and reconstitution basics: storage guide.
Questions about N-PEP-12
Is N-PEP-12 a single peptide?
No, it is a proprietary, standardized mixture of many different short peptides and amino acids derived from porcine brain protein.
What does 'porcine-derived peptone' mean?
It means the product is created by taking proteins from a pig (porcine) source—in this case, the brain—and breaking them down with enzymes into smaller peptides and amino acids. This soluble mixture is known as a peptone.
What are neurotrophic factors?
Neurotrophic factors are a family of endogenous proteins, such as BDNF and NGF, that regulate the survival, growth, differentiation, and plasticity of neurons. N-PEP-12 is studied for its ability to produce similar effects in cell culture systems.
Is N-PEP-12 for human use?
No. It is supplied strictly for in-vitro laboratory research and is not for human or animal consumption.
Related research peptides
All products are sold for laboratory research use only. Not for human consumption, not a medicine, not for diagnosing, treating or preventing any condition.