Metabolic · Synthetic Peptide Agonist
Pepcan-12
Also known as Cannabinoid Receptor 2-Selective Peptide Agonist 12
Pepcan-12 is a 12-amino acid synthetic peptide that acts as a selective agonist for the cannabinoid receptor 2 (CB2) for research purposes.
- Length
- 12 amino acids
- Half-life
- Not well characterised
- Mechanism
- Pepcan-12 is a synthetic peptide that selectively binds to and activates the cannabinoid receptor 2 (CB2).
- Studied in
- It is used in laboratory investigations to probe the function of the CB2 receptor in metabolic and inflammatory signaling pathways, separate from CB1 activity.
About Pepcan-12
Pepcan-12 is a dodecapeptide (12 amino acids) developed as a selective agonist for the cannabinoid receptor type 2 (CB2). The peptide was derived from a screening of combinatorial peptide libraries. Its selectivity for CB2 over the CB1 receptor is a key feature for research applications aimed at isolating CB2-mediated pathways.
The CB2 receptor is primarily expressed on immune cells and is involved in modulating inflammatory responses. By selectively activating CB2, Pepcan-12 serves as a research tool to study the receptor's role in cellular processes related to inflammation and metabolism. This makes it a valuable compound for in-vitro and ex-vivo models where distinguishing CB1 and CB2 effects is critical.
Laboratory notes
- Confirm CB2 receptor expression in the chosen cell line or tissue preparation to ensure a valid experimental model.
- Pepcan-12 exhibits low aqueous solubility; consider reconstitution in solvents like DMSO, followed by dilution in an appropriate aqueous buffer.
- Use appropriate control experiments, such as co-incubation with a CB2 antagonist, to verify that observed effects are CB2-mediated.
Storage and reconstitution basics: storage guide.
Questions about Pepcan-12
What is the primary target of Pepcan-12?
Pepcan-12 is a selective agonist for the cannabinoid receptor 2 (CB2).
Is Pepcan-12 derived from a natural source?
No, Pepcan-12 is a synthetic peptide identified through combinatorial library screening.
Why is Pepcan-12 sold for research use only?
Regena products, including Pepcan-12, are intended exclusively for in-vitro laboratory research and are not for human or animal consumption or administration.
Is Pepcan-12 for human use?
No. It is supplied strictly for in-vitro laboratory research and is not for human or animal consumption.
Related research peptides
All products are sold for laboratory research use only. Not for human consumption, not a medicine, not for diagnosing, treating or preventing any condition.