Cosmetic · Lipopeptide
Myristoyl Pentapeptide-11
A synthetic lipopeptide comprising five amino acids attached to myristic acid, studied in vitro for its effects on extracellular matrix components.
- Length
- 5 amino acids
- Half-life
- Not well characterised
- Mechanism
- This synthetic peptide is designed to interact with components of the extracellular matrix (ECM), such as fibronectin and elastin, in cell culture models.
- Studied in
- In vitro models, particularly fibroblast and keratinocyte cultures, are used to investigate its influence on the expression of ECM proteins.
About Myristoyl Pentapeptide-11
Myristoyl Pentapeptide-11 is a synthetic peptide containing a five amino acid sequence conjugated to a 14-carbon fatty acid, myristic acid. The lipid component is intended to enhance its stability and ability to associate with cell membranes or other lipophilic structures in experimental systems.
Laboratory research primarily utilises cell culture models, such as human dermal fibroblasts, to assess the peptide's effects on the synthesis of extracellular matrix proteins. These studies typically measure changes in the gene expression or protein levels of molecules like fibronectin and elastin following treatment.
Laboratory notes
- Solubility is enhanced in DMSO or hydro-alcoholic solutions due to the myristoyl group.
- When used in cell culture, appropriate vehicle controls (e.g., DMSO) are necessary to isolate the peptide's effects.
- Aggregation may occur in purely aqueous solutions at high concentrations; sonication may be required for solubilisation.
Storage and reconstitution basics: storage guide.
Questions about Myristoyl Pentapeptide-11
What is the function of the myristoyl group?
The myristoyl group is a fatty acid tail attached to the peptide to increase its lipophilicity, which may influence its interaction with cellular structures in laboratory assays.
What kind of research is this peptide used for?
It is primarily used in in vitro studies with skin cell cultures, like fibroblasts, to examine its effects on the production of extracellular matrix proteins.
Is Myristoyl Pentapeptide-11 a naturally occurring molecule?
No, it is a synthetic lipopeptide designed for laboratory research and cosmetic formulation screening.
Is Myristoyl Pentapeptide-11 for human use?
No. It is supplied strictly for in-vitro laboratory research and is not for human or animal consumption.
Related research peptides
All products are sold for laboratory research use only. Not for human consumption, not a medicine, not for diagnosing, treating or preventing any condition.