Cosmetic · Lipo-peptide
Myristoyl Tetrapeptide-12
A myristoylated tetrapeptide studied in vitro for its influence on keratin expression in keratinocyte cell culture models.
- Length
- 4 amino acids
- Half-life
- Not well characterised
- Mechanism
- This peptide sequence is investigated for its potential to support keratin production in isolated keratinocyte cultures.
- Studied in
- Research applications focus on its effects on keratin gene expression and protein synthesis in in vitro models of epithelial cells.
About Myristoyl Tetrapeptide-12
Myristoyl Tetrapeptide-12 is a synthetic lipo-peptide, which consists of the four-amino-acid sequence Lys-Leu-Ala-Lys (KLAK) covalently bonded to a myristic acid molecule. The myristoyl group is a C14 fatty acid that enhances the peptide's lipophilicity. This modification is designed to improve its interaction with lipid structures in experimental models.
This peptide is used as a research tool in cell biology, particularly in studies involving keratinocytes. Laboratory investigations examine its capacity to modulate the expression of specific keratin genes, such as KRT31 and KRT85, which are involved in hair fiber formation. The peptide is applied to cell cultures to observe subsequent changes in mRNA and protein levels.
Laboratory notes
- Due to the myristoyl group, solubility is higher in hydro-alcoholic solutions or emulsions rather than pure aqueous buffers.
- Store lyophilised material at -20°C. Reconstituted solutions should be stored under sterile conditions at 2-8°C for short-term use.
- Purity and identity should be confirmed by HPLC and Mass Spectrometry for research use.
Storage and reconstitution basics: storage guide.
Questions about Myristoyl Tetrapeptide-12
What is the purpose of the myristoyl group?
The myristoyl fatty acid tail increases the lipophilicity of the peptide, which is a property studied for its influence on peptide stability and interaction with cellular lipid membranes in vitro.
What type of research is this peptide used for?
It is a cosmetic-grade peptide used in laboratory research to study pathways related to keratin production in keratinocyte cell lines.
Is this peptide for human use?
No, this is a raw material intended for formulation development and laboratory research only. It is not a finished product for consumer application.
Is Myristoyl Tetrapeptide-12 for human use?
No. It is supplied strictly for in-vitro laboratory research and is not for human or animal consumption.
Related research peptides
All products are sold for laboratory research use only. Not for human consumption, not a medicine, not for diagnosing, treating or preventing any condition.